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Back to FDA Approved Medications... Estradiol for Menopause Symptoms & OsteoporosisEstradiol Estradiol Prescription Order Estradiol here... 24 Hour Prescription Delivery of your Estradiol Prescription
Chemical Name: ESTRADIOL (es-tra-DYE-ol)
This medicine is a female hormone and is
usually given to women who no longer produce the proper amount. It is used
to reduce menopause symptoms (e.g., hot flashes, vaginal dryness), to
prevent bone loss (osteoporosis) in people at high risk, and to treat other
conditions as determined by your doctor. If you are only being treated for
vaginal menopause symptoms, products applied locally such as vaginal creams,
tablets, or rings should be considered before products taken by mouth or
absorbed through the skin. There are several medicines (e.g., raloxifene or
bisphosphonates) that are safe and effective to prevent or treat bone loss.
These medicines should be considered for use before estrogen therapy. If you
have other medical conditions as well, and are prescribed estrogens for more
than one condition, consult your doctor about your treatment plan and its
options.
WARNING: Estrogens have been reported to
increase the chance of womb (endometrial) cancer in women who have been
through menopause, especially in women with a uterus who receive
estrogen-only hormone therapy. Estrogens may also increase the risk of
cancer of the ovary/breast. Estrogen-containing medicines should not be used
to prevent heart disease. Estrogen given in combination with another hormone
(progestin) for replacement therapy can infrequently cause heart disease
(e.g., heart attacks), stroke, serious blood clots, dementia, and cancer of
the breast. These risks appear to depend on the length of time this medicine
is used and the amount of estrogen per dose. Therefore, this medicine should
be used for the shortest possible length of time at the lowest effective
dose, so you obtain the benefits and minimize the chance of serious side
effects from long-term treatment. Consult your doctor or pharmacist for
details. If you use this medicine for an extended period, you should be
evaluated at least once yearly (see CAUTIONS section). This medicine is not
effective in preventing/treating a tendency toward miscarriages nor the
threat of miscarriage. This medicine must not be used during pregnancy
because its use may result in birth defects or cancer later in the child's
life (see CAUTIONS section). INFORM YOUR DOCTOR OR PHARMACIST of all
prescription and over-the-counter medicine that you are taking. ADDITIONAL
MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking
corticosteroids (e.g., prednisone), hydantoins (e.g., phenytoin), or
warfarin. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if
you are taking any medicines which may affect certain liver enyzymes
(CYP450-3A4 enzymes) including azole antifungals (e.g., ketoconazole,
itraconazole), carbamazepine, cimetidine, macrolide antibiotics (e.g.,
clarithromycin, erythromycin), phenobarbital, rifamycins (e.g., rifampin),
ritonavir, or St. John's wort. DO NOT START OR STOP ANY MEDICINE without
doctor or pharmacist approval. Inform your doctor of any other medical
conditions including a family medical history (e.g., especially breast
lumps/cancer), asthma, diabetes, seizures, migraine headaches, kidney
disease, heart disease (e.g., high blood pressure, heart attacks, congestive
heart failure), low thyroid hormone (hypothyroidism), abnormal calcium level
in the blood, depression, high blood pressure during pregnancy, yellowing of
eyes/skin during pregnancy or with past estrogen use, womb problems (e.g.,
uterine fibroids/endometriosis), cholesterol/lipid problems, gallbladder
disease, excessive weight gain, certain blood disorder (porphyria),
allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE IS NOT
RECOMMENDED if you have certain medical conditions including undiagnosed
abnormal vaginal bleeding, certain cancers (e.g., breast cancer, especially
non-metastatic type), blood clots, liver disease, or active/recent stroke or
heart attack. Contact your doctor or pharmacist if you have any questions or
concerns about taking this medicine.
Follow the directions for using this medicine
provided by your doctor. This medicine may come with a patient leaflet. Ask
your doctor, nurse, or pharmacist any questions you may have about this
medicine. The patch is usually replaced twice a week (about every 3 to 4
days), or as directed by your doctor. Follow the dosing schedule carefully.
Do not open the sealed pouch containing the patch until ready to use. Open
the pouch and remove the patch from the protective liner. Apply the patch to
a clean, dry, hairless area on the trunk (torso) or hips, usually on the
stomach or the buttocks, but not on the arms or legs. Do not apply to a site
that is exposed to sunlight. Press the patch firmly against the skin for
about 10 seconds to be sure the patch stays on. Do not place the patch on
the breast. Avoid applying to the waistline since tight clothing may rub the
patch off. Do not put the patch on areas where sitting may loosen it. When
it is time to change the patch, remove it and dispose of properly. Apply a
new patch to a different area to prevent skin irritation. It is best to
rotate the areas where the patch is applied, allowing at least 1 week in
between applications to the same site. If the area around the patch becomes
red, itchy, or irritated, try a new site. If the irritation continues or
becomes worse, notify your doctor promptly. STORE THIS MEDICINE at room
temperature according to the package instructions, in the original sealed
pouch, away from heat, moisture, and light. IF YOU MISS A DOSE OF THIS
MEDICINE, use it as soon as possible. If a patch falls off, reapply it or
apply a new patch and wear it for the rest of the scheduled period, then
resume your usual dosing schedule. Do NOT use 2 doses at once.
KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS
while you are using this medicine. You should have a complete physical
examination, including blood pressure measurements, breast and pelvic
examinations, and a PAP test (for vaginal cancer), at least once a year. You
should also have periodic mammograms as determined by your doctor. Follow
your doctor's instructions for examining your own breasts, and report any
lumps immediately. THIS MEDICINE MAY ALTER CERTAIN LAB RESULTS. Make sure
laboratory personnel and your doctors know that you are using this medicine.
If you will be having surgery or will be confined to a chair or bed for a
long period of time (e.g., a long plane flight), notify your doctor
beforehand. Special precautions may need to be taken in these circumstances
while you are taking this medicine. THIS MEDICINE MAY CAUSE DIZZINESS. DO
NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS
until you know how you react to this medicine. Using this medicine alone,
with other medicines, or with alcohol may lessen your ability to drive or to
perform other potentially dangerous tasks. LIMIT ALCOHOLIC BEVERAGES while
using this medicine. THIS MEDICINE MAY CAUSE a patchy darkening of the skin
on the face (melasma). Sunlight may intensify this darkening and you may
need to avoid prolonged sun exposure and sunlamps. Consult your doctor
regarding use of sunscreens and protective clothing. Cigarette smoking can
increase the chance of blood clots while taking this medicine (especially in
women over the age of 35). BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either
prescription or over-the-counter, check with your doctor or pharmacist.
CAUTION IS ADVISED WHEN USING THIS MEDICINE IN CHILDREN as it might stunt
their growth. If used in children, their growth pattern should be monitored.
FOR WOMEN: THIS MEDICINE HAS BEEN SHOWN TO CAUSE HARM to the human fetus. DO
NOT USE THIS MEDICINE if you are pregnant. IF YOU SUSPECT THAT YOU COULD BE
PREGNANT, contact your doctor immediately. IT IS UNKNOWN IF THIS MEDICINE IS
EXCRETED in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while taking
this medicine, check with your doctor or pharmacist to discuss the risks to
your baby.
SIDE EFFECTS, that may go away during
treatment, include dizziness, lightheadedness, headache, stomach upset,
bloating, nausea, weight changes, increased/decreased interest in sex,
breast tenderness, or skin redness/irritation at the application site. If
they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR
IMMEDIATELY if you experience mental/mood changes (e.g., severe depression,
memory loss), calf/pain swelling, sudden severe headache, chest pain,
trouble breathing, one-sided weakness, slurred speech, vision changes (e.g.,
change in contact lens fit, loss of vision), breast lumps, swelling of
hands/feet, changes in vaginal bleeding (e.g., spotting, breakthrough
bleeding, or prolonged bleeding), unusual vaginal discharge/itching/odor, or
yellowing of the eyes/skin. AN ALLERGIC REACTION to this medicine is
unlikely, but seek immediate medical attention if it occurs. Symptoms of an
allergic reaction include rash, itching, swelling, severe dizziness, or
trouble breathing. If you notice other effects not listed above, contact
your doctor, nurse, or pharmacist.
Drug interactions can result in unwanted side
effects or prevent a medicine from doing its job. Use our drug interaction
checker to find out if your medicines interact with each other. Check drug
interactions
If overdose is suspected, contact your local
poison control center or emergency room immediately. Symptoms of overdose
may include severe nausea and vomiting and excessive vaginal bleeding. Non-drug therapy to help prevent bone loss includes a weight-bearing exercise plan and adequate daily intake of calcium and vitamin D. Consult your doctor or pharmacist for more details. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out. Back to FDA Approved Medications... |